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Tarceva mechanism of action

EGFR mutation-positive and wild-type NSCLC are two genetically distinct diseases.1,2 Tarceva blocks the ATP binding pocket of the EGF receptor in both cases, but its binding capabilities differ.3,4 The new mechanism of action materials provide the latest hypothesis for the efficacy of Tarceva in EGFR Mut+ and wild-type NSCLC.

 

Mechanism of Action

Tarceva mechanism of action animation
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Dosing guidelines and management of side effects

Information on dosing and management of side effects (rash, diarrhea and ILD) are summarized in the document “Tarceva: dosing guidelines and side effect management strategies”

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Tarceva slide decks

  • First-line erlotinib in EGFR Mut+ advanced NSCLC - view
  • Erlotinib as maintenance therapy in advanced NSCLC - view
  • Second-line erlotinib in patients with advanced NSCLC - view

SmPC

The EU product label for Tarceva is available in different languages.

Mechanism of action

Mechanism of Action

Click to access and download the new Tarceva mechanism of action video.

New indication for Tarceva

Tarceva is now approved for first-line therapy of EGFR Mut+ NSCLC.

Tarceva.com

This site is only intended for use by healthcare professionals outside of the US. If you are a US resident, please visit http://www.tarceva.com/.