Tarceva mechanism of action
EGFR mutation-positive and wild-type NSCLC are two genetically distinct diseases.1,2 Tarceva blocks the ATP binding pocket of the EGF receptor in both cases, but its binding capabilities differ.3,4 The new mechanism of action materials provide the latest hypothesis for the efficacy of Tarceva in EGFR Mut+ and wild-type NSCLC.
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Tarceva mechanism of action animation |
Dosing guidelines and management of side effects
Information on dosing and management of side effects (rash, diarrhea and ILD) are summarized in the document “Tarceva: dosing guidelines and side effect management strategies”
